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Product   Name :

PCNA

Cat No. :

CSP0059

Uniprot   ID：

P12004

Gene Description：

Proliferating   cell nuclear antigen

Species：

Human

Source：

E.coli, Recombinant

Character：

Liquid

Application   :

Immunogen;   Standard; Calibrator

Concentration：

1mg/ml

Purity：

>90%

QA   Standard：

SDS PAGE

Buffer:

0.15M PBS, pH 7.5 with 50% glycerol

Storage:

-20℃ for one year

Background：

Proliferating cell nuclear antigen (PCNA) is a   DNA clamp that acts as a processivity factor for DNA polymerase δ in   eukaryotic cells and is essential for replication. PCNA is a homotrimer and   achieves its processivity by encircling the DNA, where it acts as a scaffold   to recruit proteins involved in DNA replication, DNA repair, chromatin remodeling   and epigenetics. PCNA gene is often stably and constitutively expressed in   most tissues and cells, it is commonly   used as a loading control for western blot and other test.