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  • 產(chǎn)品名稱(chēng)： Research Grade Plamotamab (帕拉莫妥單抗 )
  • 產(chǎn)品貨號： CSD00605
  • 貨期： 現貨
  • 價(jià)格與訂購： 2480
  • 數量：
    庫存： 100
  • 規格： 100μg
  • 產(chǎn)品信息
  • 如何訂購
    貨號（Catalog No.）
    CSD00605
    通用名INN
    Plamotamab
    純度(Purity)
    >95%
    濃度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    內毒素(Endotoxin level)
    Please contact with the lab for this information.
    產(chǎn)品描述(Description)
    Plamotamab (XmAb13676) is a tumor-targeted antibody that contains both a CD20 binding domain and a cytotoxic T-cell binding domain (CD3).An XmAb Bispecific Fc domain serves as the scaffold for these two antigen binding domains and confers long circulating half-life,stability and ease of manufacture on plamotamab.CD20 is highly expressed on B-cell tumor cells, including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL) cells.Engagement of CD3 by plamotamab activates T cells for highly potent and targeted killing of CD20-expressing tumor cells. The structural stability and modularity enabled by the XmAb Bispecific Fc domain allowed the tuning of plamotamab’s potency to balance anti-tumor activity with the reduction of immune toxicity that can result from T-cell activation.
    別名(Alternative names)
    XmAb-13676
    靶點(diǎn);物種(Specificity target name;species)
    CD3E/MS4A1[Homo sapiens]
    種類(lèi)(Species)
    Chimeric,Humanized
    受體鑒定(Receptor identification)
    IgG1-kappa / scFv-h-CH2-CH3
    CAS
    2138442-31-4
    存儲條件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .