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- 產(chǎn)品名稱(chēng)： Anti TMPRSS2 polyclonal antibody
- 產(chǎn)品貨號： CSP226
- 貨期： 現貨
- 價(jià)格與訂購： 2880
- 數量：
庫存： 100
- 規格：
- 產(chǎn)品信息
- 如何訂購
產(chǎn)品名稱(chēng)（Product name）
Anti TMPRSS2 polyclonal antibody
貨號（Catalog#）
CSP226icon
描述（description）
Produced in rabbits immunized with purified,Recombinant Human TMPRSS2 protein
Accession #
O15393
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別名（Alternative names)
PP9284, PRSS10, Serine protease 10, TMPRSS2
穩定性&儲存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
特異性（Spcificty）
Recognizes Human TMPRSS2 protein
亞型（Isotype）
IgG
宿主（Host）
Rabbit
克隆性（Clonality）
Polyclonal
偶連物（Conjugation）
Unconjugate
種屬反應性（Species reactivity）
Human,other species was not test
應用實(shí)驗（Tested applications）
WB,IHCiconiconicon
免疫原（Immunogen）
Recombinant Human TMPRSS2 protein
背景（Background）
TMPRSS2, also named as PRSS10, is a type II transmembrane serine protease which is highly expressed by the epithelium of the human prostate gland. TMPRSS2 may contribute to prostate tumour metastasis via the activation of PAR-2. TMPRSS2 is a Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions. TMPRSS2 as a host cell factor that is critical for spread of several clinically relevant viruses, including influenza A viruses and coronaviruses.SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming. The initial spike protein priming by TMPRSS2 is essential for entry and viral spread of SARS-CoV-2 through interaction with the ACE2 receptor.Camostat mesylate, an inhibitor of TMPRSS2, can block SARS-CoV-2 infection of lung cells.The MW of TMPRSS2 is about 65-70 kDa. It can be cleaved in to some chains with MW 54 kDa, 31 kDa and 26 kDaicon
狀態(tài)（Form）
Liquidicon
儲存溶液（Buffer）
PBS,pH7.4,containing 0.05% proclin300,50% glycerol.
濃度（Concentration）
0.5mg/mliconicon
分子量（MW）
54kDa
應用實(shí)驗及稀釋比例（Dilution Range）
WB:1:2000-1:8000,IHC:1:200-1:400
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Note
For research use only .
地 址：
產(chǎn)品銷(xiāo)售：
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郵 編：
Amily
